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NICD-mediated notch transduction regulates the different fate of chicken primordial germ cells and spermatogonial stem cells

Abstract Background Notch signaling is mainly regulated by Notch1 during development of chicken germ stem cells; however, the molecular mechanisms that contribute to generation of these germ stem cells have not been thoroughly investigated. Results In our studies, Overexpression of the Notch1 NICD p...

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Principais autores: Qisheng Zuo, Chen Zhang, Kai Jin, Jin Jing, Changhua Sun, Mahmoud F. Ahmed, Jiuzhou Song, Yani Zhang, Guohong Chen, Bichun Li
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-06-01
Serier:Cell & Bioscience
Fag:
Primordial germ cells
Spermatogonial stem cells
Notch signaling
RNA-seq
Transduction
Online adgang:http://link.springer.com/article/10.1186/s13578-018-0238-y
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