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Bis-pyrazole as receptor interacting protein 1 kinase inhibitor: Synthesis, preliminary biological evaluation against pancreatic cancer cell line and its docking studies

The pyrazole heterocycle displayed versatile pharmacological activity ranging from anti-inflammatory to antiviral. Herein, we report the synthesis of bis-pyrazole as receptor- interacting protein 1 kinase inhibitor and evaluated for antiproliferative activity against pancreatic cancer line, PANC-1....

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Principais autores: Sandeep Singh, Rajeev Kumar Sharma, R. Ramajayam
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-01-01
coleção:Results in Chemistry
Assuntos:
Pyrazole
Antiproliferative
RIP 1 kinase inhibitor
Pancreatic cancer
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211715624001437
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