Implantation of a neoantigen-targeted hydrogel vaccine prevents recurrence of pancreatic adenocarcinoma after incomplete resection

Tumor involvement of major vascular structures limits surgical options in pancreatic adenocarcinoma (PDAC), which in turn limits opportunities for cure. Despite advances in locoregional approaches, there is currently no role for incomplete resection. This study evaluated a gelatinized neoantigen-tar...

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Autors principals:	Daniel Delitto, Daniel J. Zabransky, Fangluo Chen, Elizabeth D. Thompson, Jacquelyn W. Zimmerman, Todd D. Armstrong, James M. Leatherman, Reecha Suri, Tamara Y. Lopez-Vidal, Amanda L. Huff, Melissa R. Lyman, Samantha R. Guinn, Marina Baretti, Luciane T. Kagohara, Won Jin Ho, Nilofer S. Azad, William R. Burns, Jin He, Christopher L. Wolfgang, Richard A. Burkhart, Lei Zheng, Mark Yarchoan, Neeha Zaidi, Elizabeth M. Jaffee
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2021-01-01
Col·lecció:	OncoImmunology
Matèries:	pancreatic adenocarcinoma immunotherapy neoantigen vaccine hydrogel surgery
Accés en línia:	http://dx.doi.org/10.1080/2162402X.2021.2001159
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