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Isobavachromene ameliorates insulin resistance via inactivating the MAPK/NF-κB signaling pathway

Inflammation caused by obesity, particularly in adipose tissue and the liver, can lead to insulin resistance (IR) and trigger type 2 diabetes mellitus (T2DM). It is crucial to identify therapeutic agents that alleviate IR by reducing inflammation. Here, we report that isobavachromene (IB), a flavono...

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Main Authors: Zhenhua Liu, Zhenhua Liang, Lanting Xu, Jiajia Yuan, Yiqi Li, Wenyi Kang, Yan Zhang, Bin Cong
Format: Artigo
Language:Inglês
Published: Tsinghua University Press 2025-08-01
Series:Food Science and Human Wellness
Subjects:
isobavachromene
diabetes
insulin resistance
inflammation
mapk/nf-κb
Online Access:https://www.sciopen.com/article/10.26599/FSHW.2024.9250369
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