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Bacterial Hsp90 Facilitates the Degradation of Aggregation-Prone Hsp70–Hsp40 Substrates

In eukaryotes, the 90-kDa heat shock proteins (Hsp90s) are profusely studied chaperones that, together with 70-kDa heat shock proteins (Hsp70s), control protein homeostasis. In bacteria, however, the function of Hsp90 (HtpG) and its collaboration with Hsp70 (DnaK) remains poorly characterized. To un...

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Autors principals: Bruno Fauvet, Andrija Finka, Marie-Pierre Castanié-Cornet, Anne-Marie Cirinesi, Pierre Genevaux, Manfredo Quadroni, Pierre Goloubinoff
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021-04-01
Col·lecció:Frontiers in Molecular Biosciences
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fmolb.2021.653073/full
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