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The two different isoforms of the RSC chromatin remodeling complex play distinct roles in DNA damage responses.

The RSC chromatin remodeling complex has been implicated in contributing to DNA double-strand break (DSB) repair in a number of studies. Both survival and levels of H2A phosphorylation in response to damage are reduced in the absence of RSC. Importantly, there is evidence for two isoforms of this co...

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Auteurs principaux: Anna L Chambers, Peter M Brownlee, Samuel C Durley, Tracey Beacham, Nicholas A Kent, Jessica A Downs
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2012-01-01
Collection:PLoS ONE
Accès en ligne:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0032016&type=printable
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