The F-actin modulator SWAP-70 controls podosome patterning in osteoclasts
Osteoclasts are bone resorbing cells acting as key mediators of bone disorders. Upon adhesion to bone, osteoclasts polarize and reorganize their cytoskeleton to generate a ring-like F-actin-rich structure, the sealing zone, wherein the osteoclast's resorptive organelle, the ruffled border, is formed...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016-12-01
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| coleção: | Bone Reports |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2352187216300262 |
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