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Influence of androgenic blockade with flutamide on pain behaviour and expression of the genes that encode the NaV1.7 and NaV1.8 voltage-dependent sodium channels in a rat model of postoperative pain

Abstract Background Experimental studies suggest that testosterone reduces the nociceptive response after inflammatory and neuropathic stimuli, however the underlying mechanisms have not been fully elucidated. The aims of this study were to evaluate the effect of peripheral blockade of testosterone...

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Збережено в:
Бібліографічні деталі
Автори: José Osvaldo Barbosa Neto, João Batista Santos Garcia, Maria do Socorro de Souza Cartágenes, Andressa Godoy Amaral, Luiz Fernando Onuchic, Hazem Adel Ashmawi
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2019-08-01
Серія:Journal of Translational Medicine
Предмети:
Онлайн доступ:http://link.springer.com/article/10.1186/s12967-019-2031-z
Теги: Додати тег
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