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Insights into the Design of MYC-Targeting Proteolysis Targeting Chimeras (PROTACs)

The oncogenic transcription factor MYC is a key driver of the development and progression of various types of cancer, but its intrinsically disordered structure and dependence on protein–protein interactions make it a difficult therapeutic target. Proteolysis-targeting chimeras (PROTACs) are bifunct...

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Bibliografiska uppgifter
Huvudupphov: Abdallah M. Alfayomy, Sven Hagemann, Matthias Schmidt, Ali Fouad, Mohamed Ayman El-Zahabi, Stefan Hüttelmaier, Wolfgang Sippl
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2026-03-01
Serie:Molecules
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Länkar:https://www.mdpi.com/1420-3049/31/6/1011
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