α-Heteroarylthiomethyl ketones: Small molecule inhibitors of 3CLpro
The main protease 3CLpro of the SARS-CoV-2 virus is a well--established therapeutic target for the treatment of COVID-19. In this study, we screened an in-house compound library and identified a series of α-heteroarylthiomethyl ketones as inhibitors of 3CLpro. Among these, analogues 31 and 33 emerge...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Sciendo
2025-06-01
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| Col·lecció: | Acta Pharmaceutica |
| Matèries: | |
| Accés en línia: | https://doi.org/10.2478/acph-2025-0023 |
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