ERα blockade in dendritic cells enhances antigen cross-presentation and induces antitumor CD8+ T cell immunity
Abstract Dendritic cells (DC) dysfunction impedes antitumor immunity, so understanding intrinsic regulators of DC antigen presentation and the resulting activation of antitumor CD8+ T cells could benefit therapy. Here, we use a genome-wide CRISPR screen for antigen presentation-regulating genes in D...
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| Hlavní autoři: | , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2026-05-01
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| Edice: | Nature Communications |
| On-line přístup: | https://doi.org/10.1038/s41467-026-72647-7 |
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