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Dexmedetomidine Pharmacokinetics in Neonates with Hypoxic-Ischemic Encephalopathy Receiving Hypothermia

Dexmedetomidine is a promising sedative and analgesic for newborns with hypoxic-ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). Pharmacokinetics and safety of dexmedetomidine were evaluated in a phase I, single-center, open-label study to inform future trial strategies. We rec...

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Váldodahkkit: Ryan M. McAdams, Daniel Pak, Bojan Lalovic, Brian Phillips, Danny D. Shen
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Wiley 2020-01-01
Ráidu:Anesthesiology Research and Practice
Liŋkkat:http://dx.doi.org/10.1155/2020/2582965
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