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Coagulation Factor XII Levels and Intrinsic Thrombin Generation in Multiple Sclerosis

BackgroundFactor XII (FXII) activation initiates the intrinsic (contact) coagulation pathway. It has been recently suggested that FXII could act as an autoimmunity mediator in multiple sclerosis (MS). FXII depositions nearby dentritic cells were detected in the central nervous system of MS patients...

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Principais autores: Nicole Ziliotto, Marcello Baroni, Sofia Straudi, Fabio Manfredini, Rosella Mari, Erica Menegatti, Rebecca Voltan, Paola Secchiero, Paolo Zamboni, Nino Basaglia, Giovanna Marchetti, Francesco Bernardi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-04-01
Serier:Frontiers in Neurology
Fag:
multiple sclerosis
coagulation
factor XII
intrinsic pathway
thrombin generation
Online adgang:http://journal.frontiersin.org/article/10.3389/fneur.2018.00245/full
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