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Low-density lipoprotein receptor-related protein 1 (LRP1) regulates the stability and function of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor in neurons.

The low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional endocytic receptor abundantly expressed in neurons. Increasing evidence demonstrates that LRP1 regulates synaptic integrity and function at the post synapses, at least partially by regulating glutamate receptors. The...

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Principais autores: Ming Gan, Peizhou Jiang, Pamela McLean, Takahisa Kanekiyo, Guojun Bu
格式: Artigo
语言:Inglês
出版: Public Library of Science (PLoS) 2014-01-01
丛编:PLoS ONE
在线阅读:https://doi.org/10.1371/journal.pone.0113237
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