Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Abstract The skin's unique thermosensitivity renders it exceptionally responsive to thermal perturbations, wherein heat stress exposure disrupts cutaneous homeostasis and activates pigmentary pathways. While clinical observations consistently link heat stress to hyperpigmentation disorders, the prec...

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Hauptverfasser:	Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2026-02-01
Schriftenreihe:	Advanced Science
Schlagworte:	CX3CL1 CX3CR1 H3K4me3 heat stress melanogenesis MYC
Online-Zugang:	https://doi.org/10.1002/advs.202510164
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