p66ShcA potentiates the cytotoxic response of triple-negative breast cancers to PARP inhibitors
Triple-negative breast cancers (TNBCs) lack effective targeted therapies, and cytotoxic chemotherapies remain the standard of care for this subtype. Owing to their increased genomic instability, poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) are being tested against TNBCs. In particular, cli...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , , , |
|---|---|
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Clinical investigation
2021-02-01
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| سلاسل: | JCI Insight |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1172/jci.insight.138382 |
| الوسوم: |
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