Quinuclidin-3-one-based quaternary ammonium compounds as potent antibacterials against Staphylococcus aureus and Listeria monocytogenes

Bacterial resistance and the cytotoxicity of conventional quaternary ammonium compounds (QACs) highlight the necessity for safer and more effective membrane-active antibacterials. This study aimed to synthesize a homologous series of quinuclidin-3-one-based QACs (QO-C12, QO-C14, and QO-C16) and to...

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Detalhes bibliográficos

Principais autores:	Antonio Sabljić, Doris Čarija, Karolina Begić, Renata Odžak, Rozelindra Čož-Rakovac, Josip Tomaš, Matilda Šprung
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2026-04-01
Colecção:	Biomolecules & Biomedicine
Assuntos:	Quaternary ammonium compounds QACs quinuclidin-3-one QACs bacterial resistance cytotoxicity zebrafish embryotoxicity
Acesso em linha:	https://www.bjbms.org/ojs/index.php/bjbms/article/view/14037
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