Ready, Set, Fuse! The Coronavirus Spike Protein and Acquisition of Fusion Competence

Coronavirus-cell entry programs involve virus-cell membrane fusions mediated by viral spike (S) proteins. Coronavirus S proteins acquire membrane fusion competence by receptor interactions, proteolysis, and acidification in endosomes. This review describes our current understanding of the S proteins...

Полное описание

Библиографические подробности

Главные авторы:	Tom Gallagher, Taylor Heald-Sargent
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2012-04-01
Серии:	Viruses
Предметы:	coronavirus virus entry viral pathogenesis spike protein carcinoembryonic antigen angiotensin converting enzyme 2 endocytosis cathepsin transmembrane protease membrane fusion
Online-ссылка:	http://www.mdpi.com/1999-4915/4/4/557/
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