Naked cuticle homolog 2 controls the differentiation of osteoblasts and osteoclasts and ameliorates bone loss in ovariectomized mice

Naked cuticle homolog 2 (NKD2) has been recognized as an antagonist of Wnt/β-catenin signaling and a tumor suppressor. The role of NKD2 in osteoblast and osteoclast differentiation and the mechanism are not fully understood. In this study, we identified the up-regulation of NKD2 during osteoblast an...

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Principais autores:	Liying Shan, Xiaoxia Liao, Xiaoli Yang, Endong Zhu, Hairui Yuan, Jie Zhou, Xiaoxia Li, Baoli Wang
Formato:	Artigo
Idioma:	Inglês
Publicado:	KeAi Communications Co., Ltd. 2025-01-01
Series:	Genes and Diseases
Assuntos:	Mechanistic target of rapamycin complex 1 Naked cuticle homolog 2 Osteoblast Osteoclast Receptor activator of nuclear factor κB ligand Wnt/β-catenin
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2352304224000060
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