Mathematical modeling of multicellular tumor spheroids quantifies inter-patient and intra-tumor heterogeneity
Abstract In the study of brain tumors, patient-derived three-dimensional sphere cultures provide an important tool for studying emerging treatments. The growth of such spheroids depends on the combined effects of proliferation and migration of cells, but it is challenging to make accurate distinctio...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2025-02-01
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| Serie: | npj Systems Biology and Applications |
| Accesso online: | https://doi.org/10.1038/s41540-025-00492-3 |
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