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RegIIIβ promotes Salmonella Typhimurium colonization of the gut in the early-stage gastrointestinal infection by enhancing flagella-driven locomotion.

The bactericidal lectin RegIIIβ secreted by intestinal epithelial cells, kills the microbiota and enteropathogens but also been suggested to modulate bacterial physiology and host interactions. However, it remains to be determined whether RegIIIβ plays roles beyond its bactericidal effects. The pres...

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Main Authors: Tsuyoshi Miki, Hana Yamaguchi, Momoko Kobayashi, Masahiro Ito, Takeshi Haneda, Nobuhiko Okada, Yun-Gi Kim
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2025-11-01
Series:PLoS Pathogens
Acceso en liña:https://doi.org/10.1371/journal.ppat.1013665
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