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C3a-C3aR signaling is a novel modulator of skeletal homeostasis

Osteoimmune studies have identified complement signaling as an important regulator of the skeleton. Specifically, complement anaphylatoxin receptors (i.e., C3aR, C5aR) are expressed on osteoblasts and osteoclasts, implying that C3a and/or C5a may be candidate mediators of skeletal homeostasis. The s...

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Bibliografische Detailangaben
Hauptverfasser: Megan B. Kuhn, Hayden S. VandenBerg, Andrew J. Reynolds, Matthew D. Carson, Amy J. Warner, Amanda C. LaRue, Chad M. Novince, Jessica D. Hathaway-Schrader
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2023-06-01
Schriftenreihe:Bone Reports
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2352187223000104
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