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RNAi-based gene silencing in primary mouse and human adipose tissues

Cultured adipocyte cell lines are a model system widely used to study adipose function, but they exhibit significant physiological differences compared with primary cells from adipose tissue. Here we report short interfering RNA-based methodology to selectively attenuate gene expression in mouse and...

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Principais autores: Vishwajeet Puri, Abhijit Chakladar, Joseph V. Virbasius, Silvana Konda, Aimee M. Powelka, My Chouinard, G. Nana Hagan, Richard Perugini, Michael P. Czech
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2007-02-01
coleção:Journal of Lipid Research
Assuntos:
RNA interference
mitochondrial proteins
receptor-interacting protein 140
Akt
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0022227520436831
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