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Reverse vaccinology and subtractive genomics approaches for identifying common therapeutics against Mycobacterium leprae and Mycobacterium lepromatosis

Abstract Background Mycobacterium leprae and Mycobacterium lepromatosis are gram-positive bacterial pathogens and the causative agents of leprosy in humans across the world. The elimination of leprosy cannot be achieved by multidrug therapy alone, and highlights the need for new tools and drugs to...

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Principais autores: Arun Kumar Jaiswal, Sandeep Tiwari, Syed Babar Jamal, Letícia de Castro Oliveira, Helioswilton Sales-Campos, Leonardo Eurípedes Andrade-Silva, Carlo Jose Freire Oliveira, Preetam Ghosh, Debmalya Barh, Vasco Azevedo, Siomar C. Soares, Virmondes Rodrigues Junior, Marcos Vinicius da Silva
Formato: Artigo
Idioma:Inglês
Publicado em: SciELO 2021-04-01
coleção:Journal of Venomous Animals and Toxins including Tropical Diseases
Assuntos:
Mycobacterium leprae
Mycobacterium lepromatosis
Leprosy
Vaccine targets
Drug target identification
Acesso em linha:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992021000100308&tlng=en
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