Altered duodenal N6-methyladenosine levels in common variable immunodeficiency associate with duodenal microbiota

IntroductionCommon variable immunodeficiency (CVID) is frequently complicated by duodenal inflammation, but the underlying molecular mechanisms remain poorly understood. While epigenetic alterations have been described in CVID, the epitranscriptome is largely unexplored. We therefore investigated wh...

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Bibliografiske detaljer

Principais autores:	Vegard Myhre, Mari Kaarbø, Mingyi Yang, Børre Fevang, Mirta M. L. Sousa, Henrik M. Reims, Knut E. A. Lundin, Johannes R. Hov, Pål Aukrust, Magnar Bjørås, Silje F. Jørgensen
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2026-07-01
Serier:	Frontiers in Immunology
Fag:	CVID - common variable immunodeficiency duodenum epitranscriptome analysis gastrointestinal diseases M6A modification m6A enzyme system
Online adgang:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1875823/full
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