Why is the tumor microenvironment disordered by NADH/NAD+ imbalance and how can we intervene?

NADH and NAD+ are crucial redox cofactors in biological systems, participating in the mitochondrial respiratory chain and playing significant roles in various metabolic processes. Increasing evidence indicates that changes in the NADH/NAD+ ratio play a critical role in tumor biology. In this review,...

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Bibliografische Detailangaben

Hauptverfasser:	Jing Li, Tong Zhang, Tianrong Ma, Tao Chen, Xianzhi Liu, Weiling He
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-05-01
Schriftenreihe:	Redox Biology
Schlagworte:	NADH/NAD+ Tumor metabolism Mitochondria Tumor immunity Anti-Tumor therapy
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2213231726001436
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