Benefits of sacubitril/valsartan alone and in combination with dapagliflozin in a preclinical female model of cardiometabolic and age-related cardiac dysfunction

Abstract Background Heart failure with preserved ejection fraction (HFpEF) disproportionately affects elderly women and is closely associated with central obesity and metabolic dysfunction. Although sodium-glucose co-transporter-2 inhibitors (SGLT2i) are recommended in all HFpEF patients, the potent...

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Bibliografske podrobnosti

Principais autores:	Elena Mele, Maria Antonietta Riemma, Maria Donniacuo, Marialucia Telesca, Grazia Sorrentino, Domenico D’Amario, Filippo Scialò, Eleonora Cianflone, Donato Cappetta, Daniele Torella, Giuseppe Castaldo, Francesco Rossi, Liberato Berrino, Konrad Urbanek, Antonella De Angelis
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2026-03-01
Serija:	Cardiovascular Diabetology
Teme:	Cardiometabolic HFpEF Female sex Ageing ARNi SGLT2i
Online dostop:	https://doi.org/10.1186/s12933-026-03133-z
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