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Prolonged Survival in <i>HER2</i> Mutant Metastatic NSCLC with Leptomeningeal Metastases Treated with Intrathecal Trastuzumab and Methotrexate: A Case Report

Leptomeningeal metastasis (LM) is a devastating complication of any solid organ malignancy, including nonsmall cell lung cancer (NSCLC). Human Epidermal Growth Factor Receptor2 HER2 mutant NSCLC is a rare subtype detected in only 2 to 4% cases. The occurrence of LM in HER2 mutant NSCLC is an extreme...

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Main Authors: Indranil Ghosh, Punit Sharma, Anirban Ghosh
Format: Artigo
Language:Inglês
Published: Thieme Medical and Scientific Publishers Pvt. Ltd.
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
NSCLC
HER2 mutant
CSF
leptomeningeal
trastuzumab
methotrexate
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0046-1817161
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