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A Refined Human Linear B Cell Epitope Map of Outer Surface Protein C (OspC) From the Lyme Disease Spirochete, Borrelia burgdorferi

Background: A detailed understanding of the human antibody response to outer surface protein C (OspC) of Borrelia burgdorferi has important implications for Lyme disease diagnostics and vaccines. Methods: In this report, 13 peptides encompassing 8 reported OspC linear B-cell epitopes from OspC type...

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Main Authors: Grace Freeman-Gallant, Kathleen McCarthy, Jennifer Yates, Karen Kulas, Michael Rudolph, David Vance, Nicholas J Mantis
Format: Artigo
Language:Inglês
Published: Case Western Reserve University 2025-02-01
Series:Pathogens and Immunity
Subjects:
Lyme disease
antibody
epitope
vaccine
Borrelia burgdorferi
Borreliella
Online Access:https://www.paijournal.com/index.php/paijournal/article/view/756
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