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Unveiling the therapeutic potential of exogenous β-hydroxybutyrate for chronic colitis in rats: novel insights on autophagy, apoptosis, and pyroptosis

Ulcerative colitis (UC) is a chronic relapsing inflammatory disease of the colorectal area that demonstrates a dramatically increasing incidence worldwide. This study provides novel insights into the capacity of the exogenous β-hydroxybutyrate and ketogenic diet (KD) consumption to alleviate dextran...

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Principais autores: Rasha Abdelhady, Sameh Saber, Mustafa Ahmed Abdel-Reheim, Mohannad Mohammad S. Alamri, Jaber Alfaifi, Masoud I. E. Adam, Lobna A. Saleh, Azza I. Farag, Elsayed A. Elmorsy, Hend S. El-Wakeel, Ahmed S. Doghish, Mohamed E. Shaker, Sara H. Hazem, Heba A. Ramadan, Rabab S. Hamad, Osama A. Mohammed
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2023-09-01
Serija:Frontiers in Pharmacology
Teme:
Online dostop:https://www.frontiersin.org/articles/10.3389/fphar.2023.1239025/full
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