Obesity Reprogrammes Adipose Extracellular Vesicles to Induce Muscle Atrophy via miR‐150‐5p‐Mediated Transcriptional Silencing

ABSTRACT Background Sarcopenic obesity, where excess body fat coexists with reduced muscle mass and function, is becoming increasingly common in ageing populations and contributes to poor physical and metabolic health. Although adipose tissue–secreted factors are implicated in muscle decline, the sp...

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Главные авторы:	Joshua M. J. Price, Michael Macleod, Thomas Nicholson, Caitlin M. Ditchfield, Bethy Airstone, Natalie Lachlan‐Jiraskova, Edward T. Davis, Kostas Tsintzas, Simon W. Jones
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2026-02-01
Серии:	Journal of Cachexia, Sarcopenia and Muscle
Предметы:	adipose atrophy extracellular vesicles miRNA obesity sarcopenia
Online-ссылка:	https://doi.org/10.1002/jcsm.70204
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