Mild Inactivation of RE-1 Silencing Transcription Factor (REST) Reduces Susceptibility to Kainic Acid-Induced Seizures

RE-1 Silencing Transcription factor (REST) controls several steps in neural development by modulating the expression of a wide range of neural genes. Alterations in REST expression have been associated with the onset of epilepsy; however, whether such alterations are deleterious or represent a prote...

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Principais autores:	Emanuele Carminati, Federica Buffolo, Anna Rocchi, Caterina Michetti, Fabrizia Cesca, Fabio Benfenati
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2020-01-01
סדרה:	Frontiers in Cellular Neuroscience
נושאים:	RE-1 silencing restriction factor (REST) epilepsy gene transcription light-oxygen-voltage (LOV) domain paired-amphipathic helix 1 (PAH1) domain kainic acid
גישה מקוונת:	https://www.frontiersin.org/article/10.3389/fncel.2019.00580/full
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