Terminal Uridylyltransferases TUT4/7 Regulate microRNA and mRNA Homeostasis
The terminal nucleotidyltransferases TUT4 and TUT7 (TUT4/7) regulate miRNA and mRNA stability by 3′ end uridylation. In humans, TUT4/7 polyuridylates both mRNA and pre-miRNA, leading to degradation by the U-specific exonuclease DIS3L2. We investigate the role of uridylation-dependent decay in mainta...
Kaydedildi:
| Asıl Yazarlar: | , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
MDPI AG
2022-11-01
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| Seri Bilgileri: | Cells |
| Konular: | |
| Online Erişim: | https://www.mdpi.com/2073-4409/11/23/3742 |
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