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Effect of Coxsackievirus B4 Infection on the Thymus: Elucidating Its Role in the Pathogenesis of Type 1 Diabetes

The thymus gland is a primary lymphoid organ for T-cell development. Various viral infections can result in disturbance of thymic functions. Medullary thymic epithelial cells (mTECs) are important for the negative selection of self-reactive T-cells to ensure central tolerance. Insulin-like growth fa...

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Hoofdauteurs: Abdulaziz Alhazmi, Magloire Pandoua Nekoua, Hélène Michaux, Famara Sane, Aymen Halouani, Ilka Engelmann, Enagnon Kazali Alidjinou, Henri Martens, Hela Jaidane, Vincent Geenen, Didier Hober
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2021-05-01
Reeks:Microorganisms
Onderwerpen:
viruses
enterovirus
Coxsackievirus B
thymus
self-tolerance
autoimmunity
Online toegang:https://www.mdpi.com/2076-2607/9/6/1177
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