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Association of Molecular Biomarker Heterogeneity With Treatment Pattern and Disease Outcomes in Multifocal or Multicentric Breast Cancer

PurposeThis study aimed to evaluate the rates of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki67 heterogeneity in multifocal or multicentric breast cancer (MMBC) and its association with treatment pattern and disease outcomes.MethodsMMBC...

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Principais autores: Shuai Li, Jiayi Wu, Ou Huang, Jianrong He, Weiguo Chen, Yafen Li, Xiaosong Chen, Kunwei Shen
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Assuntos:
biomarkers
breast neoplasms
intertumoral heterogeneity
multifocal
multicentric
prognosis
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fonc.2022.833093/full
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