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Hydrophilic or Lipophilic Statins?

Drugs can be classified as hydrophilic or lipophilic depending on their ability to dissolve in water or in lipid-containing media. The predominantly lipophilic statins (simvastatin, fluvastatin, pitavastatin, lovastatin and atorvastatin) can easily enter cells, whereas hydrophilic statins (rosuvasta...

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Principais autores: Elisenda Climent, David Benaiges, Juan Pedro-Botet
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-05-01
Serier:Frontiers in Cardiovascular Medicine
Fag:
adverse effects
cardiovascular disease
hydrophilic
lipophilic
pleiotropic effects
statins
Online adgang:https://www.frontiersin.org/articles/10.3389/fcvm.2021.687585/full
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