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Evaluation of AlphaFold structure-based protein stability prediction on missense variations in cancer

Identifying pathogenic missense variants in hereditary cancer is critical to the efforts of patient surveillance and risk-reduction strategies. For this purpose, many different gene panels consisting of different number and/or set of genes are available and we are particularly interested in a panel...

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Hlavní autoři: Hilal Keskin Karakoyun, Şirin K. Yüksel, Ilayda Amanoglu, Lara Naserikhojasteh, Ahmet Yeşilyurt, Cengiz Yakıcıer, Emel Timuçin, Cemaliye B. Akyerli
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2023-02-01
Edice:Frontiers in Genetics
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fgene.2023.1052383/full
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