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To Enhance Mucus Penetration and Lung Absorption of Drug by Inhalable Nanocrystals-In-Microparticles

To effectively achieve the pulmonary delivery for curcumin (CN), novel inhalable mucus-penetrating nanocrystal-based microparticles (INMP) were designed. The D-Tocopherol acid polyethylene glycol 1000 succinate (TPGS) modified CN nanocrystals (CN-NS@TPGS) were prepared by high pressure homogenizatio...

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Principais autores: Guiting Huang, Shuyuan Shuai, Weicheng Zhou, Yingchong Chen, Baode Shen, Pengfei Yue
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-02-01
coleção:Pharmaceutics
Assuntos:
nanocrystals-in-microparticles
mucus penetration
inhalation administration
TPGS
Acesso em linha:https://www.mdpi.com/1999-4923/14/3/538
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