In search of causal variants: refining disease association signals using cross-population contrasts

<p>Abstract</p> <p>Background</p> <p>Genome-wide association (GWA) using large numbers of single nucleotide polymorphisms (SNPs) is now a powerful, state-of-the-art approach to mapping human disease genes. When a GWA study detects association between a SNP and the disease, this signal usually repres...

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Detalhes bibliográficos

Principais autores:	Rice John P, Hinrichs Anthony L, Grucza Richard A, Goate Alison M, Saccone Scott F, Saccone Nancy L, Bierut Laura J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2008-08-01
Colecção:	BMC Genetics
Acesso em linha:	http://www.biomedcentral.com/1471-2156/9/58
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