Obinutuzumab in the treatment of idiopathic refractory membranous nephropathy: an observational case series

ObjectiveIdiopathic refractory membranous nephropathy (IRMN) is a subset of nephrotic syndrome with a high risk of progression to end-stage renal disease, yet treatment options remain limited. Obinutuzumab, a humanized type II anti-CD20 antibody, induces efficient CD20+ cell depletion, leading to fa...

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Detalhes bibliográficos

Principais autores:	Xiangling Zhao, Xuejie Chang, Yuejuan Wang, Duqun Chen, Manshu Yu, Jing Zhao, Hong Zhu, Yan Mao, Chenxia Juan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-02-01
coleção:	Frontiers in Medicine
Assuntos:	anti-PLA2R antibodies CD20 B cells + idiopathic refractory membranous nephropathy obinutuzumab PLA2R antibody
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1704970/full
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