A rise in prepubertal DHEA in the spiny mouse reveals the effect of adrenarche on the reproductive axis

Abstract Background Adrenarche, characterized by rising adrenal dehydroepiandrosterone (DHEA) levels, precedes puberty and has been implicated in reproductive maturation, and disorders like polycystic ovary syndrome (PCOS). However, the mechanisms by which DHEA influences the hypothalamic-pituitary–...

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Bibliografische gegevens

Hoofdauteurs:	Maya Sudman, Hadas Gruber, Ben Bar-Sadeh, Tal Refael, Gil Golan, Nicol Shvartsman, Lilach Pnueli, Noga Kronfeld-Schor, Philippa Melamed
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2026-05-01
Reeks:	BMC Biology
Onderwerpen:	DHEA Adrenarche Puberty Hypothalamus Ovary Steroidogenesis
Online toegang:	https://doi.org/10.1186/s12915-026-02619-2
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