Single Domain Antibodies as Carriers for Intracellular Drug Delivery: A Proof of Principle Study

Antibody-drug conjugates (ADCs) are currently used for the targeted delivery of drugs to diseased cells, but intracellular drug delivery and therefore efficacy may be suboptimal because of the large size, slow internalization and ineffective intracellular trafficking of the antibody. Using a phage d...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Sebas D. Pronk, Erik Schooten, Jurgen Heinen, Esra Helfrich, Sabrina Oliveira, Paul M. P. van Bergen en Henegouwen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-06-01
coleção:	Biomolecules
Assuntos:	single-domain antibody internalization intracellular drug delivery ADC
Acesso em linha:	https://www.mdpi.com/2218-273X/11/7/927
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!