Analysis of three-dimensional chromatin packing domains by chromatin scanning transmission electron microscopy (ChromSTEM)

Abstract Chromatin organization over multiple length scales plays a critical role in the regulation of transcription. Deciphering the interplay of these processes requires high-resolution, three-dimensional, quantitative imaging of chromatin structure in vitro. Herein, we introduce ChromSTEM, a meth...

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Bibliografiske detaljer

Principais autores:	Yue Li, Vasundhara Agrawal, Ranya K. A. Virk, Eric Roth, Wing Shun Li, Adam Eshein, Jane Frederick, Kai Huang, Luay Almassalha, Reiner Bleher, Marcelo A. Carignano, Igal Szleifer, Vinayak P. Dravid, Vadim Backman
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2022-07-01
Serier:	Scientific Reports
Online adgang:	https://doi.org/10.1038/s41598-022-16028-2
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