IL-17RA Promotes Cigarette Smoke-Induced Alveolar Epithelial Cell Pyroptosis in COPD via Dual Activation of the NLRP3/Caspase1/GSDMD and NF-κB/GSDME Pathways

Xuan An, Yanhui Gu, Jian Zhou, Yuting Liu, Shengyi Yu, Lanying Zhang, Yao Ouyang Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, People’s Republic of ChinaCorrespondence: Yao Ouyang, Email ouyangyao116@sohu.comBackground:...

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Detalhes bibliográficos

Principais autores:	An X, Gu Y, Zhou J, Liu Y, Yu S, Zhang L, Ouyang Y
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Dove Medical Press 2026-06-01
Colecção:	Journal of Inflammation Research
Assuntos:	IL-17A IL-17RA GSDMD GSDME Pyroptosis COPD
Acesso em linha:	https://www.dovepress.com/il-17ra-promotes-cigarette-smoke-induced-alveolar-epithelial-cell-pyro-peer-reviewed-fulltext-article-JIR
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