Defense-associated reverse transcriptases define an emerging class of noncanonical DNA-writing systems

Defense-associated reverse transcriptases (DRTs) are emerging as a mechanistically diverse class of bacterial antiviral enzymes. Rather than acting simply as RNA-to-DNA copying proteins, they generate a wide range of unconventional DNA products, including de novo gene-assembling cDNAs, random single...

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Библиографические подробности

Главный автор:	Yaojun Tong
Формат:	Artigo
Язык:	Inglês
Опубликовано:	KeAi Communications Co., Ltd. 2026-12-01
Серии:	Synthetic and Systems Biotechnology
Предметы:	Defense-associated reverse transcriptase (DRT) Antiphage immunity DNA synthesis Noncanonical polymerization Synthetic biology Nucleic acid engineering
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2405805X26001365
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