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Distinct populations of vascular smooth muscle and sinoatrial progenitors are localized adjacent to pro-epicardium

Summary: The developmental potential of cells adjacent to pro-epicardial (PE) cells (pro-EpiCs) that also express pro-EpiC markers is unknown. We apply single-cell mRNA deep sequencing paired with RNAScope validation, bioinformatic analysis, and lineage tracing to determine the heterogeneity and spe...

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Hauptverfasser: Lianjie Miao, Anika Nusrat, Jian Li, Changhong Yin, Yangyang Lu, Xianyan Kuang, Daizong Sun, Edward Lo, Renjie Song, Weihua Huang, Xiaochun Long, Bradley K. McConnell, Harold A. Singer, Robert J. Schwartz, Preethi Gunaratne, Zhen-Chuan Fan, Ashok Kumar, Bin Zhou, Nikhil Munshi, Sylvia M. Evans, Mingfu Wu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2025-12-01
Schriftenreihe:Cell Reports
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S221112472501352X
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