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Synthesis, Reactions and Biological Evaluation of Some New Naphtho[2,1-b]furan Derivatives Bearing a Pyrazole Nucleus

Vilsmeier formylation of 2-(1-phenylhydrazonoethyl)naphtho[2,1-b]furan (2) gave 3-naphtho[2,1-b]furan-2-yl-1-phenyl-1H-pyrazole-4-carbaldehyde (3), which was reacted with C- and N-nucleophiles to afford naphthofuranpyrazol derivatives 4-8. Treatment of 2-[(3-(naphtho[2,1-b]furan-2-yl)-1-phenyl-1H-py...

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Principais autores: Ahemed M. El-Agrody, Fawzy M. Ali, Ahmed H. A. Halawa, Ashraf H. F. Abd El-Wahab, Zarrag Isa A. Al-Fifi, Ahmed H. Bedair
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2011-01-01
Serier:Molecules
Fag:
Vilsmeier reaction
2-[3-(naphtho[2,1-b]furan-2-yl)-1-phenyl-1H-pyrazol-4-yl)methylene]malononitrile
1,3,4-thiadiazol-2-ylacetamide
antimicrobial activity
Online adgang:http://www.mdpi.com/1420-3049/16/1/307/
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