Identification and validation of key modules and hub genes associated with the pathological stage of oral squamous cell carcinoma by weighted gene co-expression network analysis

Background Oral squamous cell carcinoma (OSCC) is a major lethal malignant cancer of the head and neck region, yet its molecular mechanisms of tumourigenesis are still unclear. Patients and methods We performed weighted gene co-expression network analysis (WGCNA) on RNA-sequencing data with clinical...

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Principais autores:	Xuegang Hu, Guanwen Sun, Zhiqiang Shi, Hui Ni, Shan Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado:	PeerJ Inc. 2020-02-01
Series:	PeerJ
Assuntos:	Oral squamous cell carcinoma (OSCC) Weighted gene co-expression network analysis (WGCNA) Hub gene Pathologic stage Overall survival
Acceso en liña:	https://peerj.com/articles/8505.pdf
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