BAK/BAX-Mediated Apoptosis Is a Myc-Induced Roadblock to Reprogramming
Summary: Despite intensive efforts to optimize the process, reprogramming differentiated cells to induced pluripotent stem cells (iPSCs) remains inefficient. The most common combination of transcription factors employed comprises OCT4, KLF4, SOX2, and MYC (OKSM). If MYC is omitted (OKS), reprogrammi...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018-02-01
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| Colecção: | Stem Cell Reports |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2213671117305672 |
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