Injectable rhBMP-2-loaded calcium phosphate cement and chitosan composite hydrogel for the repair of osteoporotic bone defects

Abstract Background Regeneration of osteoporotic bone defects is a major clinical challenge due to impaired osteogenic activity and high infection risks. We developed an injectable rhBMP-2-loaded calcium phosphate cement (CPC) and chitosan (CH) composite hydrogel (rhBMP-2/CPC@CH) to evaluate its the...

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Principais autores:	Minglei Cai, Jian Huang, Fulong Zhong, Bowen Lai, Jing Wang, Tielong Liu
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-03-01
Series:	BMC Musculoskeletal Disorders
Assuntos:	Osteoporosis rhBMP-2 Chitosan Calcium phosphate cement Hydrogel Bone regeneration
Acceso en liña:	https://doi.org/10.1186/s12891-026-09717-w
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